MovDisordV3, France, Analysis, bibRecord, 000381

Chemical exposures and Parkinson's disease: A population‐based case–control study

Identifieur interne : 000381 ( France/Analysis ); précédent : 000380; suivant : 000382

Chemical exposures and Parkinson's disease: A population‐based case–control study

Auteurs : Roberta Frigerio [États-Unis] ; Kevin R. Sanft [États-Unis] ; Brandon R. Grossardt [États-Unis] ; Brett J. Peterson [États-Unis] ; Alexis Elbaz [France] ; James H. Bower [États-Unis] ; J. Eric Ahlskog [États-Unis] ; Mariza De Andrade [États-Unis] ; Demetrius M. Maraganore [États-Unis] ; Walter A. Rocca [États-Unis]

Source :

Movement Disorders [ 0885-3185 ] ; 2006-10.

RBID : ISTEX:D3F86333A56D5DDEB68FC621E8253E8B8382EC76

Descripteurs français

Pascal (Inist)
- Etude cas témoin, Parkinson maladie, Pesticide, Sexe, Système nerveux pathologie.
Wicri :
- topic : Pesticide.

English descriptors

KwdEn :
- Adult, Aged, Aged, 80 and over, Agriculture, Case control study, Case-Control Studies, Causality, Educational Status, Female, Health Surveys, Humans, Male, Middle Aged, Minnesota, Nervous system diseases, Parkinson Disease (diagnosis), Parkinson Disease (epidemiology), Parkinson Disease (etiology), Parkinson disease, Parkinson's disease, Parkinsonian Disorders (chemically induced), Parkinsonian Disorders (diagnosis), Pesticides, Pesticides (toxicity), Risk Factors, Sex, Smoking (adverse effects), case–control study, chemical exposures, pesticides, sex differences.
MESH :
- chemical , toxicity : Pesticides.
- geographic : Minnesota.
- adverse effects : Smoking.
- chemically induced : Parkinsonian Disorders.
- diagnosis : Parkinson Disease, Parkinsonian Disorders.
- epidemiology : Parkinson Disease.
- etiology : Parkinson Disease.
- Adult, Aged, Aged, 80 and over, Agriculture, Case-Control Studies, Causality, Educational Status, Female, Health Surveys, Humans, Male, Middle Aged, Risk Factors.

Abstract

The putative association between pesticide exposures and Parkinson's disease (PD) remains controversial. We identified all subjects who developed PD in Olmsted County, Minnesota, from 1976 through 1995, and matched them by age (± 1 year) and sex to general population controls. We assessed exposures to chemical products by means of telephone interview with cases, controls, or their proxies (149 cases; 129 controls). Exposure to pesticides related or unrelated to farming was associated with PD in men (odds ratio, 2.4; 95% confidence interval, 1.1–5.4; P = 0.04). The association remained significant after adjustment for education or smoking. Analyses for the other six categories of industrial and household chemicals were all nonsignificant. This population‐based study suggests a link between pesticides use and PD that is restricted to men. Pesticides may interact with other genetic or nongenetic factors that are different in men and women. © 2006 Movement Disorder Society

Url:

DOI: 10.1002/mds.21009

Affiliations:

Links to Exploration step

ISTEX:D3F86333A56D5DDEB68FC621E8253E8B8382EC76

Le document en format XML

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<term>Case-Control Studies</term>
<term>Causality</term>
<term>Educational Status</term>
<term>Female</term>
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<term>Parkinsonian Disorders (chemically induced)</term>
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<term>Pesticides</term>
<term>Pesticides (toxicity)</term>
<term>Risk Factors</term>
<term>Sex</term>
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<term>case–control study</term>
<term>chemical exposures</term>
<term>pesticides</term>
<term>sex differences</term>
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<term>Aged, 80 and over</term>
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<term>Case-Control Studies</term>
<term>Causality</term>
<term>Educational Status</term>
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<front><div type="abstract" xml:lang="en">The putative association between pesticide exposures and Parkinson's disease (PD) remains controversial. We identified all subjects who developed PD in Olmsted County, Minnesota, from 1976 through 1995, and matched them by age (± 1 year) and sex to general population controls. We assessed exposures to chemical products by means of telephone interview with cases, controls, or their proxies (149 cases; 129 controls). Exposure to pesticides related or unrelated to farming was associated with PD in men (odds ratio, 2.4; 95% confidence interval, 1.1–5.4; P = 0.04). The association remained significant after adjustment for education or smoking. Analyses for the other six categories of industrial and household chemicals were all nonsignificant. This population‐based study suggests a link between pesticides use and PD that is restricted to men. Pesticides may interact with other genetic or nongenetic factors that are different in men and women. © 2006 Movement Disorder Society</div>
</front>
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<tree><country name="États-Unis"><region name="Minnesota"><name sortKey="Frigerio, Roberta" sort="Frigerio, Roberta" uniqKey="Frigerio R" first="Roberta" last="Frigerio">Roberta Frigerio</name>
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<name sortKey="Ahlskog, J Eric" sort="Ahlskog, J Eric" uniqKey="Ahlskog J" first="J. Eric" last="Ahlskog">J. Eric Ahlskog</name>
<name sortKey="Bower, James H" sort="Bower, James H" uniqKey="Bower J" first="James H." last="Bower">James H. Bower</name>
<name sortKey="De Andrade, Mariza" sort="De Andrade, Mariza" uniqKey="De Andrade M" first="Mariza" last="De Andrade">Mariza De Andrade</name>
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<name sortKey="Peterson, Brett J" sort="Peterson, Brett J" uniqKey="Peterson B" first="Brett J." last="Peterson">Brett J. Peterson</name>
<name sortKey="Rocca, Walter A" sort="Rocca, Walter A" uniqKey="Rocca W" first="Walter A." last="Rocca">Walter A. Rocca</name>
<name sortKey="Rocca, Walter A" sort="Rocca, Walter A" uniqKey="Rocca W" first="Walter A." last="Rocca">Walter A. Rocca</name>
<name sortKey="Sanft, Kevin R" sort="Sanft, Kevin R" uniqKey="Sanft K" first="Kevin R." last="Sanft">Kevin R. Sanft</name>
</country>
<country name="France"><noRegion><name sortKey="Elbaz, Alexis" sort="Elbaz, Alexis" uniqKey="Elbaz A" first="Alexis" last="Elbaz">Alexis Elbaz</name>
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Movement Disorders (revue)

Chemical exposures and Parkinson's disease: A population‐based case–control study

Chemical exposures and Parkinson's disease: A population‐based case–control study

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.